Yuan X, Braunstein EM, Ye Z, Liu FF, Chen G, Zou J, Cheng L† and Brodsky RA†.  Generation of GPI Anchor Protein Deficient Blood Cells from Human Induced Pluripotent Stem Cells. Stem Cells: Translational Medicine, in press (†Both are corresponding authors).

Ye Z†, Liu CF, Piterkova L, Dowey SN, He C, Huang X, Brodsky RA, Spivak JL, Prchal JT and Cheng L†. Differential sensitivity to JAK inhibitory drugs by isogenic human erythroblasts and hematopoietic progenitors generated from patient iPSCs. Stem Cells, accepted, August 2nd, 2013. (†Both are corresponding authors).

Huang X, Shah S, Wang J, Ye Z, Dowey SN, Tsang KM, Mendelsohn L, Kato GJ, Kickler T, Cheng L. Extensive Ex Vivo Expansion of Functional Human Erythroid Precursors Established from Umbilical Cord Blood Cells by Defined Factors.  Molecular Therapy (the official journal of ASGCT), published online Sept. 3rd, 2013, doi: 10.1038/mt.2013.201.

Wang Y, Chou BK, Dowey SN, He C, Gerecht S†, Cheng L†. Scalable expansion of human induced pluripotent stem cells in the defined xeno-free E8 medium under adherent and suspension culture conditions.  Stem Cell Research, 11(3):1103-1116 (†Both are corresponding authors).

Yan W, Smith C and Cheng L. Expanded activity of dimer nucleases by combining ZFN and TALEN for genome editing.  Scientific Reports (a Nature Publication Group open-access journal), Aug 7 2013; 3:2376. doi: 10.1038/srep02376.

Kusuma S, Shen Y-I, Hanjaya-Putra D, Mali P, Cheng L, Gerecht S. Self-Organized Vascular Networks from Human Pluripotent Stem Cells in a Synthetic Matrix. PNAS, 110(31):12601-6.

Dowey SN, Huang X, Chou BK, Ye Z, Cheng L (Oct 2012) Generation of integration-free human induced pluripotent stem cells from postnatal blood mononuclear cells by plasmid vector expression. 7(11):2013-21.

Ye Z, Chou BK, Cheng L (Jun 2012) Promise and challenges of human iPSC-based hematologic disease modeling and treatment.  Int J Hematol. 95:601-609.

Cheng L, Hansen NF, Zhao L, Du Y, Zou C, Donovan FX, Chou BK, Zhou G, Li S, Dowey SN, Ye Z; NISC Comparative Sequencing Program, Chandrasekharappa SC, Yang H, Mullikin JC, Liu PP (Mar 2012) Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrated plasmid expression. Cell Stem Cell. 10(3):337-44.

Zou C, Chou BK, Dowey SN, Tsang K, Huang X, Liu CF, Smith C, Yen J, Mali P, Zhang YA, Cheng L, Ye Z (Feb 2012) Efficient Derivation and Genetic Modifications of Human Pluripotent Stem Cells on Engineered Human Feeder Cell Lines. Stem Cells Dev.  Epub 2012 Feb 15.

Cheng L, Blazar B, High K, Porteus M (Oct 2011) Zinc fingers hit off target. Nat Med. 17(10):1192-3.

Mali P, Cheng L (Sep 2011) Human Cell Engineering: Cellular Reprogramming and Genome Editing. Stem Cells.  30(1):75-81. Epub 2011 Sept 08.

Choi SM, Liu H, Chaudhari P, Kim Y, Cheng L, Feng J, Sharkis S, Ye Z, Jang YY (Aug 2011) Reprogramming of EBV-immortalized B-lymphocyte cell lines into induced pluripotent stem cells. Blood. 118 (7):1801-5.

Zou J, Mali P, Huang X, Dowey SN, Cheng L (Aug 2011) Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease. Blood. 118(17):4599-608. Epub 2011 Aug 31.

Jang YY, Ye Z, Cheng L (Apr 2011). Molecular imaging and stem cell research. Mol Imaging. 10(2):111-22.

Zou J, Sweeney CL, Chou BK, Choi U, Pan J, Wang H, Dowey SN, Cheng L, Malech HL. Oxidase deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease mediated safe harbor targeting.  Blood. 117(21):5561-72. Epub 2011 Mar 16.

Broxmeyer HE, Lee MR, Hangoc G, Cooper S, Prasain N, Kim YJ, Mallett C, Ye Z, Witting S, Cornetta K, Cheng L, Yoder MC (Mar 2011). Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21-23.5 year cryopreserved cord blood. Blood. 117(18):4773-7. Epub 2011 Mar 10.

Chou BK, Mali P, Huang X, Ye Z, Dowey SN, Resar LMS, Zou C, Zhang YA, Tong J and Cheng L (Mar 2011).

Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Research, 21(3):518-29. Epub 2011 Jan 18.

Li D, Zhou J, Wang L, Shin ME, Su P, Lei X, Kuang H, Guo W, Yang H, Cheng L, Tanaka TS, Leckband DE, Reynolds AB, Duan E, Wang F (Nov 2010). Integrated biochemical and mechanical signals regulate multifaceted human embryonic stem cell function. Journal of Cell Biology, 191(3):631-44.

Ohm JE*, Mali P*, VanNeste L*, Berman DM, Liang L, Briggs K, Pandiyan K, Zhang W, Argani P, Simons B, Yu W, Matsui W, Van Criekinge W, Zambidis E, Rassool F, Schuebel K, Cope L, Yen J, Mohammad H, Cheng L+, Baylin SB+ (2010). Cancer-related Epigenome Changes Associated with Reprogramming to Induced Pluripotent Stem Cells. Cancer Research, 70(19):7662-73. PMCID: PMC2980296. (*Equal contributions; +Co-corresponding authors).

Swistowski A, Peng J, Liu Q, Mali P, Rao MS, Cheng L, and Zeng X(2010). Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions. Stem Cells, 28(10):1893-1904. PMID: 20715183

Ye Z and Cheng L (2010). Potential of human iPS cells derived from blood and other postnatal cell types. Regenerative Medicine, (4):521-530 (invited review). PMID: 20632856.

Kerr CL, Cheng L (2010).  Multiple, interconvertible states of human pluripotent stem cells. Cell Stem Cell,  6(6):497-9.

Zou J, Cochran R, Cheng L (Mar 2010) Double knockouts in human embryonic stem cells., Cell Research, 20 (3), 250-2

Mali P, Chou BK, Yen J, Ye Z, Zou J, Dowey S, Brodsky RA, Ohm JE, Yu W, Baylin SB, Yusa K, Bradley A, Meyers DJ, Mukherjee C, Cole PA, Cheng L (Mar 2010) Butyrate Greatly Enhances Derivation of Human Induced Pluripotent Stem Cells by Promoting Epigenetic Remodeling and the Expression of Pluripotency-Associated Genes., Stem Cells (Dayton, Ohio)

Kerr CL, Cheng L (Feb 2010) The dazzle in germ cell differentiation., Journal of Molecular Cell Biology, 2(1), 26-9

Mali P, Ye Z, Chou BK, Yen J, Cheng L (2010) An improved method for generating and identifying human induced pluripotent stem cells., Methods in Molecular Biology (Clifton, N.J.), 636, 191-205

Ye Z, Zhan H, Mali P, Dowey S, Williams DM, Jang YY, Dang CV, Spivak JL, Moliterno AR, Cheng L (Dec 2009) Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders., Blood, 114 (27), 5473-80

Zou J, Maeder ML, Mali P, Pruett-Miller SM, Thibodeau-Beganny S, Chou BK, Chen G, Ye Z, Park IH, Daley GQ, Porteus MH, Joung JK, Cheng L (Jul 2009) Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells., Cell Stem Cell, 5 (1), 97-110

Pomper MG, Hammond H, Yu X, Ye Z, Foss CA, Lin DD, Fox JJ, Cheng L (Mar 2009) Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models., Cell Research, 19 (3), 370-9

Durai M, Krueger C, Ye Z, Cheng L, Mackensen A, Oelke M, Schneck JP (Feb 2009) In vivo functional efficacy of tumor-specific T cells expanded using HLA-Ig based artificial antigen presenting cells (aAPC)., Cancer Immunology, Immunotherapy : CII, 58 (2), 209-20

Savage WJ, Barber JP, Mukhina GL, Hu R, Chen G, Matsui W, Thoburn C, Hess AD, Cheng L, Jones RJ, Brodsky RA (Jan 2009) Glycosylphosphatidylinositol-anchored protein deficiency confers resistance to apoptosis in PNH., Experimental Hematology, 37 (1), 42-51

Hwang NS, Varghese S, Lee HJ, Zhang Z, Ye Z, Bae J, Cheng L, Elisseeff J (Dec 2008) In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells., Proceedings of the National Academy of Sciences of the United States of America, 105 (52), 20641-6

Hillion J, Dhara S, Sumter TF, Mukherjee M, Di Cello F, Belton A, Turkson J, Jaganathan S, Cheng L, Ye Z, Jove R, Aplan P, Lin YW, Wertzler K, Reeves R, Elbahlouh O, Kowalski J, Bhattacharya R, Resar LM (Dec 2008) The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies?, Cancer Research, 68 (24), 10121-7

Mali P, Ye Z, Hammond HH, Yu X, Lin J, Chen G, Zou J, Cheng L (May 2008) Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts., Stem Cells (Dayton, Ohio)

Yu X, Zou J, Ye Z, Hammond H, Chen G, Tokunaga A, Mali P, Li YM, Civin C, Gaiano N, Cheng L (May 2008) Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment., Cell Stem Cell, 2 (5), 461-71

Chen G, Ye Z, Yu X, Zou J, Mali P, Brodsky RA, Cheng L (Apr 2008) Trophoblast differentiation defect in human embryonic stem cells lacking PIG-A and GPI-anchored cell-surface proteins., Cell Stem Cell, 2 (4), 345-55

Cheng L (Feb 2008) More new lines of human parthenogenetic embryonic stem cells., Cell Research, 18 (2), 215-7

Ye Z, Yu X, Cheng L (2008) Lentiviral gene transduction of mouse and human stem cells., Methods in Molecular Biology (Clifton, N.J.), 430, 243-53

Cheng L, Xiao L, Zeng F, Zhang YA (Jan 2008) Stem cells shine in Shanghai., Cell stem cell, 2 (1), 34-7

Gao P (2007) HIF-dependent Anti-tumorigenic Effect of Anti-oxidants In Vivo, Cancer Cell, 12 (3), 230-238

Li L, Piloto O, Kim KT, Ye Z, Nguyen HB, Yu X, Levis M, Cheng L, Small D (Apr 2007) FLT3/ITD expression increases expansion, survival and entry into cell cycle of human haematopoietic stem/progenitor cells., British journal of haematology, 137 (1), 64-75

Zhou BY, Ye Z, Chen G, Gao ZP, Zhang YA, Cheng L (Mar 2007) Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer., Stem cells (Dayton, Ohio), 25 (3), 779-89

Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, Cope L, Mohammad HP, Chen W, Daniel VC, Yu W, Berman DM, Jenuwein T, Pruitt K, Sharkis SJ, Watkins DN, Herman JG, Baylin SB (Feb 2007) A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing., Nature genetics, 39 (2), 237-42

Cai L, Ye Z, Zhou BY, Mali P, Zhou C, Cheng L (Jan 2007) Promoting human embryonic stem cell renewal or differentiation by modulating Wnt signal and culture conditions., Cell research, 17 (1), 62-72

Mali P, Cheng L (2006) Re-programming somatic cells without fusion or ethical confusion (an invited review), Regenerative Medicine, 1 (6), 837

Dravid G, Ye Z, Hammond H, Chen G, Pyle A, Donovan P, Yu X, Cheng L (2006) Defining the role of Wnt/beta-catenin signaling in the survival, proliferation and self-renewal of human embryonic stem cells, Stem Cells, 23 (7), 1489

Cheng L (2006) Ethics: China already has clear stem-cell guidelines, Nature, 440, 992

Dravid G, Hammond H, Cheng L (2006) Culture of human embryonic stem cells on human and mouse feeder cells., Methods in molecular biology (Clifton, N.J.), 331, 91-104

Cheng L (2005) Experimental protocols section offers expert insights for stem cell research (editorial), Stem Cells, 23, 297-298

Du X, Et Al., Radiofrequency-enhanced Vascular Gene Transduction and Expression for Intravascular MR Imaging-guided Therapy: Feasibility Study in Pigs, Radiology, 236(3), 939-44, Sep 2005

Zhan X, Dravid G, Ye Z, Hammond H, Shamblott M, Gearhart J, Cheng L, Functional Antigen-presenting Leucocytes Derived From Human Embryonic Stem Cells in Vitro, Lancet, 364(9429), 163-71, Jul 2004

Pan F, Ye Z, Cheng L, Liu JO ( Apr 2004) Myocyte Enhancer Factor 2 Mediates Calcium-dependent Transcription of The Interleukin-2 Gene in T Lymphocytes: a Calcium Signaling Module That Is Distinct From But Collaborates With the Nuclear Factor of Activated T Cells (NFAT), The Journal of Biological Chemistry, 279 (15), 14477-80

Chen HH, Zhan X, Kumar A, Du X, Hammond H, Cheng L, Yang X ( Nov-Dec 2004) Detection of Dual-gene Expression in Arteries Using An Optical Imaging Method, Journal of Biomedical Optics, 9 (6), 1223-9

Cui Y, Kelleher E, Straley E, Fuchs E, Gorski K, Levitsky H, Borrello I, Civin CI, Schoenberger SP, Cheng L, Pardoll DM, Whartenby KA, Immunotherapy of established tumors using bone marrow transplantation with antigen gene--modified hematopoietic stem cells, Nature Medicine, 9(7), 952-8, July 2003

Zhou X, Cui Y, Huang X, Yu Z, Thomas AM, Ye Z, Pardoll DM, Jaffee EM, Cheng L, Lentivirus-mediated gene transfer and expression in established human tumor antigen-specific cytotoxic T cells and primary unstimulated T cells, Human Gene Therapy, 14(11), 1089-105, July 2003

Yu X, Zhan X, D&#146, Costa J, Tanavde VM, Ye Z, Peng T, Malehorn MT, Yang X, Civin CI and Cheng L, Lentiviral Vectors with Two Independent Internal Promoters Transfer High-Level Expression of Multiple Transgenes to Human Hematopoietic Stem-Progenitor Cells, Molecular Therapy, 7(6), 827, June 2003

Angelopoulou M, Novelli E, Grove JE, Henry M. Rinder M, Civin C, Cheng L, Krause DS, Cotransplantation Of Human Mesenchymal Stem Cells Enhances Human Myelopoiesis And Megakaryocytopoiesis In NOD/SCID Mice, Experimental Hematology, 31(5), 413, May 2003

Cheng L, Hammond H, Ye Z, Zhan X, Dravid G, Human Adult Marrow Cells Support Prolonged Expansion of Human Embryonic Stem Cells in Culture, Stem Cells (Dayton, Ohio), 21(2), 131-42, 2003

Cui Y, Golob J, Kelleher E, Ye Z, Pardoll D, Cheng L, Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells, Blood, 99(2), 399-408, January 2002

Yang X, Atalar E, Li D, Serfaty JM, Wang D, Kumar A, Cheng L, Magnetic resonance imaging permits in vivo monitoring of catheter-based vascular gene delivery, Circulation, 104(14), 1588-90, 2001

Yang X, Liu H, Li D, Zhou X, Jung WC, Deans AE, Cui Y, Cheng L, Digital optical imaging of green fluorescent proteins for tracking vascular gene expression: feasibility study in rabbit and human cell models, Radiology, 219(1), 171-5, April 2001

Shamblott MJ, Axelman J, Littlefield JW, Blumenthal PD, Huggins GR, Cui Y, Cheng L, Gearhart JD (2001) Human embryonic germ cell derivatives express a broad range of developmentally distinct markers and proliferate extensively in vitro, Proceedings of the National Academy of Sciences (USA), 113-8 pages

Gao Z, Golob J, Tanavde VM, Civin CI, Hawley RG, Cheng L, High levels of transgene expression following transduction of long-term NOD/SCID-repopulating human cells with a modified lentiviral vector, Stem Cells, 19(3), 247-59, 2001

Cheng L, Qasba P, Vanguri P, Thiede MA (July 2000) Human mesenchymal stem cells support megakaryocyte and pro-platelet formation from CD34(+) hematopoietic progenitor cells, Journal of Cellular Physiology, 184 (1), 58-69

Liu X, Rapp N, Deans R, Cheng L, Molecular cloning and chromosomal mapping of a candidate cytokine gene selectively expressed in human CD34 cells, Genomics, 65(3), 283-92, 2000

Novelli EM, Cheng L, Yang Y, Leung W, Ramirez M, Tanavde V, Enger C, Civin CI, Ex vivo culture of cord blood CD34 cells expands progenitor cell numbers, preserves engraftment capacity in nonobese diabetic/severe combined immunodeficient mice, and enhances retroviral transductio, Human Gene Therapy, 10(18), 2927-40, 1999

Mbalaviele G, Jaiswal N, Meng A, Cheng L, Van Den Bos C, Thiede M, Human mesenchymal stem cells promote human osteoclast differentiation from CD34 bone marrow hematopoietic progenitors, Endocrinology, 140(8), 3736-43, August 1999

Cheng L, Du C, Lavau C, Chen S, Tong J, Chen BP, Scollay R, Hawley RG, Hill B, Sustained gene expression in retrovirally transduced, engrafting human hematopoietic stem cells and their lympho-myeloid progeny, Blood, 92(1), 83-92, 1998

Cheng L, Du C, Murray D, Tong X, Zhang YA, Chen BP, Hawley RG, A GFP reporter system to assess gene transfer and expression in human hematopoietic progenitor cells, Gene Therapy, 4(10), 1013-22, October 1997

Cheng L, Fu J, Tsukamoto A, Hawley RG, Use of green fluorescent protein variants to monitor gene transfer and expression in mammalian cells, Nature Biotechnology, 14(5), 606-9, May 1996

Cheng L, Gearing DP, White LS, Compton DL, Schooley K, Donovan PJ, Role of leukemia inhibitory factor and its receptor in mouse primordial germ cell growth, Development, 120(11), 3145-53, November 1994

Resnick JL, Bixler LS, Cheng L, Donovan PJ, Long-term proliferation of mouse primordial germ cells in culture, Nature, 359(6395), 550-1, 1992

Cheng LZ, Workman JL, Kingston RE, Kelly TJ (1992) Regulation of DNA replication in vitro by the transcriptional activation domain of GAL4-VP16, Proceedings of the National Academy of Sciences (USA), 589-93 pages

Cheng L, Kelly TJ, Transcriptional activator nuclear factor I stimulates the replication of SV40 minichromosomes in vivo and in vitro, Cell, 59(3), 541-51, 1989

Dravid G, Ye Z, Hammond H, Chen G, Pyle A, Donovan P, Yu X, Cheng L, Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells., Stem cells (Dayton, Ohio), 23 (10), 1489-501

Wang K, Xue T, Tsang SY, Van Huizen R, Wong CW, Lai KW, Ye Z, Cheng L, Au KW, Zhang J, Li GR, Lau CP, Tse HF, Li RA, Electrophysiological properties of pluripotent human and mouse embryonic stem cells., Stem cells (Dayton, Ohio), 23 (10), 1526-34